Ahmed Eissa, Ahmed Zoeir, Silvia Ciarlariello, Luca Sarchi, Maria C Sighinolfi, Ahmed Ghaith, Stefano Puliatti, Raffaele Inzillo, Luca Reggiani Bonetti, Mino Rizzo, Bernardo Rocco, Salvatore Micali
- PMID: 32003203
- DOI: 10.23736/S0393-2249.20.03551-1
Abstract
Background: In endoscopic resection of colorectal tumors, the pathological assessment of the lateral margins is a strong predictor of tumor recurrence after resection. The aim of the current study is to evaluate the value of the peritumoral margins assessment in ERBT on tumor recurrence.
Methods: We retrospectively analyzed the data of 50 consecutive patients with NMIBC and treated by ERBT between January and December 2017.
Results: The lateral margins showed dysplasia in 16 patients and malignancy in three patients. Local recurrence occurred in 14 (28%) patients. It was noted that 57% of patients with recurrence showed some degree of dysplasia or malignancy in the lateral margin; however, on multivariate logistic regression lateral margins lesions were not significantly associated with recurrence (OR 2.175, 95% CI: 0.430-10.996, P=0.35).
Conclusions: ERBT may improve the pathological report of bladder tumor. There was a trend toward increased rate of recurrence in patients with dysplasia or malignancy in their lateral margins; however, this was not statistically significant on multivariate analysis. Further studies with larger sample sizes are required to assess the value of lateral margin analysis.
